Bioprocess Scale-up: From Lab to Production Scale

Language: English
Location: Garching near Munich
Duration: 4.5 days in 1 week
Start: 22 February 2027
Cost: 3,290 EUR
Bioprocess Scale-up is an onsite certificate program for mid- to lower-level management professionals in industrial biotechnology who are responsible for transferring processes between the laboratory and industrial production. The program focuses on one of biotechnology’s greatest challenges: translating promising laboratory results into reliable, cost-efficient, and scalable industrial processes, while using scale-down approaches to identify and resolve production issues more quickly and cost-effectively.

Participants learn the key principles of scale-up and scale-down, including similarity theory, scaling laws, dimensional analysis, bioreactor design, biocatalysts, CFD, technology transfer, and troubleshooting, while also exploring real industry examples, emerging tools, and new methodologies. The program is especially relevant to professionals working in white biotechnology sectors such as food, cosmetics, and household, while also offering valuable insights for practitioners across other biotechnology domains.

By combining academic expertise, industry perspectives, and real-world examples, the program equips participants with practical tools to improve process performance, reduce costly trial-and-error, and support successful industrial implementation.

This certificate program has been developed in collaboration with EuroTeQ Engineering University and is a part of the Erasmus+ microcredentials initiative focused on Green and Digital skills, co-funded by the European Union.

Quick Info

Here you will find all the information you need for this course.

Benefits

01

1

Perform Scaling with High Success Rate

Two-way transfer: translate laboratory results into reliable, cost-efficient industrial processes and successfully adapt industrial processes back to the laboratory scale.

02

2

Academic and Industrial Expertise

Benefit from the combined expertise of academic and industry leaders, ensuring both scientific excellence and practical applicability.

03

3

TUM Certificate

Receive an official certificate from the renowned Technical University of Munich (TUM), validating your knowledge and skills gained during the program.

Program Overview

Here you will find all key information about the program. The following details on the curriculum, program structure, and faculty reflect the program’s current state. As part of our commitment to continuous improvement, the program is regularly reviewed and updated to incorporate the latest academic insights and evolving needs of professional practice.
After completing the program, you will be able to confidently scale bioprocesses from laboratory development to industrial manufacturing. You will gain the knowledge and practical tools to optimize scale-up strategies, manage technology transfer, solve process challenges, and apply advanced methods such as CFD simulation to improve process performance. Through industry-relevant case studies, you will learn how to translate scientific innovation into efficient and scalable production.

By the end of the program, you will be able to:
  • Apply key bioprocess scaling principles, methods, and critical process parameters to enable effective transfer between laboratory and industrial scales in both scale-up and scale-down contexts.
  • Evaluate and optimize bioprocess performance across scales by assessing bioreactor designs and operating conditions, predicting the impact of biocatalyst population changes, and integrating sterility, downstream processing, and analytical requirements into scaling decisions.
  • Use Computational Fluid Dynamics (CFD) to analyze and optimize mixing, flow behavior, oxygen transfer, and other factors that influence large-scale process performance.
  • Troubleshoot bioprocess implementation and technology transfer by identifying common scale-up challenges, diagnosing process issues, implementing effective solutions, and ensuring successful transfer from development to commercial manufacturing.
  • Assess real bioprocessing practices and emerging technologies to identify opportunities and future directions for process development and manufacturing decisions.

Program:

Bioprocess Scale-up: From Lab to Production Scale

Target group:

Professionals in mid- to lower-management roles who are responsible for overseeing and facilitating the transfer of biotechnology processes from laboratory to industrial scale, and vice versa. Examples of such roles include, but are not limited to, team leads, senior scientists, engineers, and managers. This program is particularly suitable for professionals working in white biotechnology (e.g., food, household, and cosmetics industries), although participation is not limited to this sector.

If you are unsure whether you meet the criteria or are generally interested in the program, please do not hesitate to contact us for a personalized consultation. Send us a message via the contact form.

Academic
responsibility:

Prof. Dr. Michael Zavrel, Professorship for Bioprocess Engineering at the TUM Campus Straubing

Format & Timing:

4.5 days in 1 week

Study location:

Garching near Munich

Language:

English

Dates:

22 – 26 February 2027

Application
Deadline:

22 January 2027

Admission
Requirements:

MSc or PhD (or equivalent) and professional experience in one of the fields – biotechnology, biomanufacturing,  technical microbiology, biochemical or bioprocess engineering.

Graduation:

After successful completion you receive a certificate from the Technical University of Munich.

ECTS:

2 ECTS

Program fee:

3,290 EUR*

Discount:

10% discount for TUM Alumni and members or employees of our strategic cooperation partners

*Based on our experience, the German tax benefits help many participants self-finance their education, as these can be worth up to 50% of tuition fees and program-related travel costs. Please consult your tax advisor for more details. For participants of our programs residing outside Germany this might be applicable, please check the situation with the local tax authorities in your country of residence.  
Prof. Dr. Michael Zavrel
Professorship for Bioprocess Engineering at the TUM Campus Straubing
Prof. Dr. Alexander Gruenberger
KIT Professorship in Microsystems in Bioprocess Engineering
Program Agenda*
Day 1
  • Introduction to Bioprocess Engineering
  • Fundamentals, frameworks and tools for scaling
  • Dimension Analysis
  • Rules and challenges in scaling
Day 2
  • Bio catalysts and workflow
  • Scaling periphery: sterility, analytical measurements, and downstream processing
  • Bioprocessing facilities tour
Day 3
  • Computational Fluid Dynamics (CFD)
  • Scaling down
  • Exercises
  • Invited Expert Talk (CFD)
Day 4
  • Technology Transfer
  • Trouble shooting
  • Emerging tools and innovation
  • Exercises
  • Panel discussion with industry experts (white, red, and custom applications)
Day 5
  • Emerging tools and innovation
  • Reflection & Q&A

*Program agenda is subject to change

Partner

EuroTeQ Engineering University

Erasmus+ Program of the European Union

Info Sessions

Learn more about our certificate program Bioprocess Scale-up: From lab to production scale. The info session takes place once a year, a few months before the program starts. The dates will be announced in due time.

  • 20

    Oct | 2026
    5:00 – 6:00 PM

    Virtual Masterclass | Bioprocess Scale-Up: From Lab to Production Scale

    Get a sneak peek at the program. Sign up for our masterclass and learn more about bioprocess engineering and scaling up bioprocesses for the production phase.

Application for Bioprocess Scale-up

  • Your contact

    Karina Korekova
    Learning & Development Expert
    Phone: +49 89 289 28475
    Get in touch

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